My Little Pony: Generations was the last of our G4 comics before the G5 comics began, and the trade paperback that takes all five chapters and combines them into one book. We posted about the Amazon listing a while back, and it is now up on iTunes with the usual three page preview and confirmed release date of August 2022. Considering Discord has invaded the G5 comics, it probably isn't the end of the mane 6 in book form, but it is technically their last full dedicated arc together.
Anyway, you can find the preview below and feel free to discuss what you thought of it all!
Thanks to Edward for the heads up.
From iTunes